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Figure 3 | Silence

Figure 3

From: A status report on RNAi therapeutics

Figure 3

Comparison of on- and off-target effects. A putative lead molecule was tested in vitro to evaluate potency against the intended target, transthyretin and four sequence-related off targets defined by the bioinformatic screen. The percentage reduction in transythyretin levels was measured by quantitative PCR.

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