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Figure 1 | Silence

Figure 1

From: A structural-based statistical approach suggests a cooperative activity of PUM1 and miR-410 in human 3'-untranslated regions

Figure 1

Identification of motifs enriched among low-accessibility targets of micro (mi)RNA family μ: the complete process. Given a miRNA family and its binding sites in 3'-untranslated regions (predicted by TargetScan), we extracted sequence elements such that the seed binding site (red V in the figure) was placed in the middle surrounded by 70 base pairs upstream and downstream. We ranked these sequences according to the global accessibility score of μ, and searched for enriched motifs. The motif UGUAUAUAU was found to be enriched among miR-410 low-accessibility targets.

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Silence

ISSN: 1758-907X