Skip to main content

Table 1 Structural statistics for the 10 lowest energy-minimized conformers of Drosha-double-stranded RNA-binding domain (dsRBD)

From: Solution structure of the Drosha double-stranded RNA-binding domain

Statistic

Value

NOE distance restraints:

 

Intraresidue

98

Sequential

111

Medium range (i, i + 2 to 4)

74

Long range (i, i>4)

206

Total

489

Dihedral restraints:

189

Hydrogen bond (HBDA):

27

Ensemble RMSD:

 

Backbone secondary structure

0.44

Heavy atoms secondary structure

0.86

Violations:

 

NOE

0

Dihedral

0

HBDA

1.4

RMS experimental:

 

NOE

0.02 ± 0.005

Dihedral

0.415 ± 0.077

HBDA

0.006 ± 0.006

RMS covalent geometry:

 

Bonds

0.003 ± 0.000

Angles

0.514 ± 0.009

Impropers

0.362 ± 0.013

Ramachandran space:

 

Most favored region

81.6%

Additionally allowed

17.0%

Generously allowed

1.4%

Disallowed

0

  1. HBDA = hydrogen bond distance angle; NOE = nuclear Overhauser effect; RMSD = root mean square deviation.