Figure 1From: Experimental design, preprocessing, normalization and differential expression analysis of small RNA sequencing experimentsFlowchart of typical data-handling steps for small RNA (sRNA) libraries. Flowchart depicting the steps involved in creating, processing and normalizing next-generation sequencing libraries. In this article, we focus on sRNA data, but the methods for analyzing other RNA-based or even chromatin immunoprecipitation sequencing data are similar.Back to article page