Figure 6From: Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2False prediction of thousands of hits by seed method. Although we found an enrichment of heptamer seed matches to transforming growth factor-β receptor 2 (TGFBR2) in the hit population (left), only 2% of all small interfering (si)RNAs with heptamer seed matched scored as hits (right).Back to article page