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Figure 1 | Silence

Figure 1

From: A 5′-uridine amplifies miRNA/miRNA* asymmetry in Drosophilaby promoting RNA-induced silencing complex formation

Figure 1

Fly miRNA tend to start with U. Each miRNA or miRNA* isoform derived from a common pre-miRNA was weighted according to its abundance in the pooled deep-sequencing libraries, and the sequence composition analyses for all small RNA from different pre-miRNA that were read at least 100 times in the pooled libraries were weighted equally. Gray, nucleotide frequency at position 1; white, 100 sets of nucleotides randomly selected from nt 1-18 of the miRNA and miRNA* species to assess the overall nucleotide composition of miRNA and miRNA*. Each random set had the same size as the corresponding set of miRNA or miRNA* 5′-nt. P values measure the probability of picking a random set from nt 1-18 with the same nucleotide frequency as the actual set of 5′-nt.

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